Files in this Data Supplement:

• Supplemental file 1 - Details of plasmids and primers used, overview of in vivo experiments, and full numeric data, which are presented in graphical form in the text and supplemental figures (Tables S1 to S9).
  Zipped Ms Word document, 23K.
• Supplemental file 2 - Diagram of suicide plasmids (Fig. S1); comparison of qPCR and colony counts (Fig. S2); graphical display of results from in vivo experiments I-3, I-4, IV-1, IV-2, IV-3, and IV-4 (Fig. S3 and S4).
  Zipped PDF file, 3.9K.