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AEM Accepts, published online ahead of print on 3 October 2008
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Appl. Environ. Microbiol. doi:10.1128/AEM.01378-08
Copyright (c) 2008, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved.

Identification of a novel genomic island specific for hospital-acquired CC17 Enterococcus faecium

E. Heikens*, W. van Schaik, H. L. Leavis, M. J.M. Bonten, and R. J.L. Willems

Department of Medical Microbiology, University Medical Center Utrecht, Utrecht, The Netherlands

* To whom correspondence should be addressed. Email: E.heikens{at}umcutrecht.nl.


   Abstract

Hospital-acquired CC17 Enterococcus faecium are genetically distinct from indigenous strains and enriched with resistance genes and virulence genes. We identified a genomic island in CC17 E. faecium tentatively encoding a metabolic pathway involved in carbohydrate transport and metabolism, which may provide a competitive advantage over the indigenous E. faecium microbiota.







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