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Appl Environ Microbiol, June 1998, p. 2287-2290, Vol. 64, No. 6
0099-2240/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.

Evaluation of Lacticin 3147 and a Teat Seal Containing This Bacteriocin for Inhibition of Mastitis Pathogens

Máire P. Ryan,1,2 William J. Meaney,3 R. Paul Ross,1,* and Colin Hill2

Dairy Products Research Centre1 and Dairy Production Department,3 Teagasc, Moorepark, Fermoy, County Cork, and Department of Microbiology and National Food Biotechnology Centre, University College, Cork,2 Ireland

Received 19 December 1997/Accepted 29 March 1998

Lacticin 3147 is a broad-spectrum bacteriocin produced by Lactococcus lactis subsp. lactis DPC3147 which is bactericidal against a range of mastitis-causing streptococci and staphylococci. In this study, both lacticin 3147 and the lantibiotic nisin were separately incorporated into an intramammary teat seal product. The seal containing lacticin 3147 exhibited excellent antimicrobial activity and might form the basis of an improved treatment for the prevention of mastitis in dry cows.

* Corresponding author. Mailing address: Dairy Products Research Centre, Moorepark, Fermoy, County Cork, Ireland. Phone: 353-25-42229. Fax: 353-25-42340. E-mail: pross{at}dpc.teagasc.ie.

Appl Environ Microbiol, June 1998, p. 2287-2290, Vol. 64, No. 6
0099-2240/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.


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