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Appl. Environ. Microbiol., 12 1995, 4209-4214, Vol 61, No. 12
Copyright © 1995, American Society for Microbiology

Bioconversion of 2,4-diamino-6-nitrotoluene to a novel metabolite under anoxic and aerobic conditions

PC Gilcrease and VG Murphy
Department of Chemical and Bioresource Engineering, Colorado State University, Fort Collins 80523, USA.

Under nitrate-reducing, nongrowth conditions, a Pseudomonas fluorescens species reduced 2,4,6-trinitrotoluene to aminodinitrotoluenes, which were then further reduced to diaminonitrotoluenes. 2,4-Diamino-6- nitrotoluene (2,4-DANT) was further transformed to a novel metabolite, 4-N-acetylamino-2-amino-6-nitrotoluene (4-N-AcANT), while 2,6-diamino-4- nitrotoluene (2,6-DANT) was persistent. Efforts to further degrade 2,4- DANT and 2,6-DANT under aerobic, nitrogen-limited conditions were unsuccessful; 2,6-DANT remained persistent, and 2,4-DANT was again transformed to the 4-N-AcANT compound.

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