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Appl Environ Microbiol. 1989 September; 55(9): 2195-2199

New modified trichothecenes accumulated in solid culture by mutant strains of Fusarium sporotrichioides.

Northern Regional Research Center, U.S. Department of Agriculture, Peoria, Illinois 61604.

ABSTRACT

Mutant strains of Fusarium sporotrichioides NRRL 3299 deficient in the ability to synthesize T-2 toxin were examined on solid rice medium. Five novel alicyclic trichothecenes were isolated: 11 alpha-hydroxytrichodiene; tricho-9-ene-2 alpha,3 alpha,11 alpha-triol; tricho-9-ene-2 alpha,3 alpha,8 alpha,11 alpha-tetraol; tricho-9-ene-2 alpha,3 alpha,8 beta,11 alpha-tetraol; and tricho-9-ene-2 alpha,3 alpha,11 alpha,16-tetraol.

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