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Appl Environ Microbiol. 1971 July; 22(1): 61-65
Copyright © 1971 American Society for Microbiology. All Rights Reserved.

Inactivation of Thirty Viruses by Gamma Radiation ¹

Virology Branch, Division of Microbiology, Food and Drug Administration, Cincinnati, Ohio 45226

ABSTRACT

Decimal reduction values (D value) for 30 viruses were determined. The weighted D values of the viruses suspended in Eagle's minimum essential medium ranged from 0.39 to 0.53 Mrads. It was necessary to increase the radiation dose by a factor of >3 to inactivate virus suspended in Eagle's minimum essential medium as compared to the same virus suspended in distilled water. The destruction rate curves were of a first-order reaction.

¹ Part of the research reported here was done by Robert Sullivan in partial fulfillment of the requirements for the Ph.D. degree from the Department of Civil and Environmental Engineering, University of Cincinnati, Cincinnati, Ohio.