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Appl Environ Microbiol. 1971 July; 22(1): 11-12
Copyright © 1971 American Society for Microbiology. All Rights Reserved.

In Vitro Susceptibility of Strains of Pseudomonas pseudomallei to Rifampin

Department of Veterinary Microbiology, Division of Veterinary Medicine, Walter Reed Army Institute of Research, Washington, D.C. 20012

ABSTRACT

Reported high activity of rifampin for Pseudomonas pseudomallei could not be verified by extensive in vitro tests conducted with 31 recently isolated strains. Minimal inhibitory concentrations of rifampin were 25 µg/ml for three strains and greater than 25 µg/ml for 28 strains. Rifampin had relatively poor in vitro activity when compared with tetracycline drugs and chloramphenicol antibiotics now commonly used for treating melioidosis.

¹ Present address: Grumman Aerospace Corp., Goddard Space Flight Center, Greenbelt, Md. 20771.