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Appl Environ Microbiol. 1971 July; 22(1): 100-101
Copyright © 1971 American Society for Microbiology. All Rights Reserved.

Radiometric Method for Detection of Bacteremia

Department of Microbiology, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55901

ABSTRACT

A study was performed with simulated blood cultures to evaluate the production of ¹⁴CO₂ as an index of bacterial growth. With a range of inoculum sizes from 4 to 4,250 colony-forming units, it was not possible to detect ¹⁴CO₂ within 6 hr after inoculation in 59 separate experiments. In a limited trial with patients' blood cultures, the radiometric method failed to provide any earlier evidence of bacteremia than did routine broth cultures.