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Appl Environ Microbiol. 1970 August; 20(2): 259-262
Copyright © 1970 American Society for Microbiology. All Rights Reserved.

Rapid Semiquantitative Method for Screening Large Numbers of Virus Samples by Negative Staining Electron Microscopy

John L. Smith Memorial for Cancer Research, Chas. Pfizer & Co., Inc., Maywood, New Jersey 07607

ABSTRACT

A rapid, semiquantitative method for screening large numbers of virus samples by negative staining electron microscopy is presented. Results obtained by this method are compared with results obtained by the pseudoreplica method and a measureddrop method. A figure is presented which represents the limit of detectability for virus by negative staining.

¹ Present address: Department of Microbiology, Southern Illinois University, Carbondale, Ill.