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Appl Environ Microbiol. 1970 July; 20(1): 72-74
Copyright © 1970 American Society for Microbiology. All Rights Reserved.

Simple Method of Evaluating Scrapie in Mice

Kenneth W. Cochran and Lois B. Allen

Department of Epidemiology and Virus Laboratory, School of Public Health, University of Michigan, Ann Arbor, Michigan 48104

ABSTRACT

Mice in advanced scrapie characteristically clasp their hindlegs together. As the disease progresses into the clasping stage, mice exhibit a sequence of identifiable hindleg reactions which have categorized and assigned relative scores permitting objective, quantitative evaluation of disease.

Appl Environ Microbiol. 1970 July; 20(1): 72-74
Copyright © 1970 American Society for Microbiology. All Rights Reserved.





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Copyright © 1970 by the American Society for Microbiology. All rights reserved.