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Appl Environ Microbiol. 1970 March; 19(3): 451-454
Copyright © 1970 American Society for Microbiology. All Rights Reserved.

Thermal Inactivation of Newcastle Disease Virus ¹

Department of Nutrition and Food Science, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139

ABSTRACT

The rate of destruction of hemagglutinins and infectivity of Newcastle disease virus was determined over a temperature range of 37.8 to 60 C. From the calculated values of H and S, it was concluded that inactivation of the hemagglutinating activity and viral infectivity was due to protein denaturation.

² Present address: Department of Microbiology, University of New Hampshire, Durham, N.H. 03824.

¹ This is contribution no. 1542 from the Department of Nutrition and Food Science, Massachusetts Institute of Technology, Cambridge, Mass.