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Appl Environ Microbiol. 1970 February; 19(2): 329-334
Copyright © 1970 American Society for Microbiology. All Rights Reserved.

Spectra of Susceptibility of Neisseria meningitidis to Antimicrobial Agents In Vitro ¹

Bacteriology Division, Naval Medical Research Unit No. 4, Great Lakes, Illinois 60088

ABSTRACT

The minimal inhibitory concentrations of 49 antimicrobial agents for 37 to 40 meningococcal strains freshly isolated from the nasopharynx of healthy carriers were determined. Coumermycin A₁ and rifampin were the most effective agents tested. The geometric mean values of the minimal inhibitory concentrations for coumermycin A₁ and rifampin were 0.0001 and 0.02 µg/ml, respectively.

¹ This investigation made in connection with Research Project M4305.01-1011, Bureau of Medicine and Surgery, Navy Department, Washington, D.C.