This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Alert me to new issues of the journal Download to citation manager Reprints and Permissions Copyright Information Books from ASM Press MicrobeWorld Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Zbinovsky, V. Articles by Patterson, E. L. Search for Related Content PubMed Articles by Zbinovsky, V. Articles by Patterson, E. L. Agricola Articles by Zbinovsky, V. Articles by Patterson, E. L.

 Previous Article  |  Next Article 

Appl Environ Microbiol. 1968 April; 16(4): 614-616
Copyright © 1968 American Society for Microbiology. All Rights Reserved.

Isolation and Characterization of Antibiotic LL-AC541

Lederle Laboratories, A Division of American Cyanamid Co., Pearl River, New York 10965

ABSTRACT

A new basic, water-soluble antibiotic designated LL-AC541, produced by a strain of Streptomyces hygroscopicus (NRRL 3111), was isolated as a hydrochloride salt; []_D²⁵, — 58°, melting point, 200 to 215 C (decomposition). It is structurally related to streptothricin but does not contain ß-lysine. Isolation procedures, physicochemical properties, antimicrobial spectrum, and in vivo testing results are presented. Another very closely related antibiotic obtained from the same fermentation is briefly described.