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Appl Environ Microbiol. 1962 May; 10(3): 185-189

The Effect of Nitric Oxide on Bacteria

J. L. Shank, J. H. Silliker and R. H. Harper

Research Laboratories, Swift and Company, Chicago, Illinois

ABSTRACT

Nitric oxide, as well as several other oxides of nitrogen, were assayed for their antibacterial action. It is shown that nitric oxide has virtually no effect on bacteria, whereas both NaNO3 and NaNO2 appear to have either neutral or stimulatory effects. It is suggested that the formation of nitrous acid is mainly responsible for the quantitative as well as the qualitative changes that occur in the bacterial flora of cured meat. A pH-dependent "nitrite cycle" is presented to account for the production of nitrous acid in cured meat systems.

Appl Environ Microbiol. 1962 May; 10(3): 185-189






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